What is in vitro fertilization?
IVF involves taking eggs from the woman, fertilizing them in the laboratory
with her partner's sperm and transferring the resulting embryos back to her
uterus 2-6 (usually 3 or 5) days later.
The first IVF baby 'Louise Brown' in the world was born in July of 1978 in
England. Today, many thousands of children are born annually as a result of
this technique.
Who should be treated with in vitro fertilization?
In vitro fertilization can be used as an effective treatment for infertility
of all causes except for women with infertility caused by an anatomic problem
with the uterus, such as severe intrauterine adhesions.
It is generally used in couples who have failed to conceive after at least
one year of trying who also have one or more of the following:
- Failed 2-6 cycles of ovarian stimulation with intrauterine insemination
- Severe male factor infertility (low sperm count or low motility)
- Advanced female age - over 38
- Severe endometriosis
- Blocked fallopian tubes or pelvic adhesions with distorted pelvic anatomy.
Women that have had tubal ligation and are considering tubal reversal surgery
as well as men that are considering vasectomy reversal surgery might also
consider IVF.
- Reduced ovarian reserve, which means lower quantity (and sometimes quantity)
of eggs. A day 3 FSH and estradiol test and antral follicle counts are often
done as screening tests for egg quantity (and quality). Reduced egg quantity
and quality is usually treated with either IVF, or with IVF using egg donation
from another woman.
Conventional IVF
Intracytoplasmic sperm injection (ICSI)
With ejaculated sperms as well as testicular sperms obtained after testicular
sperm extraction (TESE), testicular
sperm aspiration (TESA), percutaneous
epididymal sperm aspiration (PESA).
Cryopreservation of embryos.
In patients with ovarian failure IVF with
donor oocytes is also available.